Precise localisation of three intra-RNA cross-links in 23S RNA and one in 5S RNA, induced by treatment of Escherichia coli 50S ribosomal subunits with bis-(2-chloroethyl)-methylamine.

Treatment of E. coli 50S ribosomal subunits with low doses of bis-(2-chloroethyl)-methylamine ("nitrogen mustard") leads to formation of a number of intra-RNA and RNA-protein cross-links. After partial digestion of the cross-linked subunits with cobra venom nuclease, followed by destructio...

Full description

Saved in:
Bibliographic Details
Main Authors: Stiege, W, Zwieb, C, Brimacombe, R
Format: Artigo
Language:Inglês
Published: 1982
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC326999/
https://ncbi.nlm.nih.gov/pubmed/6818528
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items