Notch Promotes Dynamin-Dependent Endocytosis of Nephrin

Notch signaling in podocytes causes proteinuria and glomerulosclerosis in humans and rodents, but the underlying mechanism remains unknown. Here, we analyzed morphologic, molecular, and cellular events before the onset of proteinuria in newborn transgenic mice that express activated Notch in podocyt...

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Bibliografiska uppgifter
Huvudupphovsmän: Waters, Aoife M., Wu, Megan Yi Jun, Huang, Yi-Wei, Liu, Guang Ying, Holmyard, Doug, Onay, Tuncer, Jones, Nina, Egan, Sean E., Robinson, Lisa A., Piscione, Tino D.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society of Nephrology 2012
Ämnen:
Brief Communication
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3269920/
https://ncbi.nlm.nih.gov/pubmed/22052054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2011010027
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