Notch Promotes Dynamin-Dependent Endocytosis of Nephrin

Notch signaling in podocytes causes proteinuria and glomerulosclerosis in humans and rodents, but the underlying mechanism remains unknown. Here, we analyzed morphologic, molecular, and cellular events before the onset of proteinuria in newborn transgenic mice that express activated Notch in podocyt...

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Detalhes bibliográficos
Main Authors: Waters, Aoife M., Wu, Megan Yi Jun, Huang, Yi-Wei, Liu, Guang Ying, Holmyard, Doug, Onay, Tuncer, Jones, Nina, Egan, Sean E., Robinson, Lisa A., Piscione, Tino D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Nephrology 2012
Assuntos:
Brief Communication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3269920/
https://ncbi.nlm.nih.gov/pubmed/22052054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2011010027
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