Genotype-informed estimation of risk of coronary heart disease based on genome-wide association data linked to the electronic medical record

BACKGROUND: Susceptibility variants identified by genome-wide association studies (GWAS) have modest effect sizes. Whether such variants provide incremental information in assessing risk for common 'complex' diseases is unclear. We investigated whether measured and imputed genotypes from a...

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Bibliografiska uppgifter
Huvudupphovsmän: Ding, Keyue, Bailey, Kent R, Kullo, Iftikhar J
Materialtyp: Artigo
Språk:Inglês
Publicerad: BioMed Central 2011
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3269823/
https://ncbi.nlm.nih.gov/pubmed/22151179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2261-11-66
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