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Genotype-informed estimation of risk of coronary heart disease based on genome-wide association data linked to the electronic medical record
BACKGROUND: Susceptibility variants identified by genome-wide association studies (GWAS) have modest effect sizes. Whether such variants provide incremental information in assessing risk for common 'complex' diseases is unclear. We investigated whether measured and imputed genotypes from a...
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| Главные авторы: | , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
BioMed Central
2011
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3269823/ https://ncbi.nlm.nih.gov/pubmed/22151179 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2261-11-66 |
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