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Genotype-informed estimation of risk of coronary heart disease based on genome-wide association data linked to the electronic medical record
BACKGROUND: Susceptibility variants identified by genome-wide association studies (GWAS) have modest effect sizes. Whether such variants provide incremental information in assessing risk for common 'complex' diseases is unclear. We investigated whether measured and imputed genotypes from a...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
BioMed Central
2011
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| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3269823/ https://ncbi.nlm.nih.gov/pubmed/22151179 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2261-11-66 |
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