Characterization of a pediatric T-cell acute lymphoblastic leukemia patient with simultaneous LYL1 and LMO2 rearrangements

Translocation of the LYL1 oncogene are rare in T-cell acute lymphoblastic leukemia, whereas the homologous TAL1 gene is rearranged in approximately 20% of patients. Previous gene-expression studies have identified an immature T-cell acute lymphoblastic leukemia subgroup with high LYL1 expression in...

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Bibliographische Detailangaben
Hauptverfasser: Homminga, Irene, Vuerhard, Maartje J., Langerak, Anton W., Buijs-Gladdines, Jessica, Pieters, Rob, Meijerink, Jules P.P.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Ferrata Storti Foundation 2012
Schlagworte:
Original Articles and Brief Reports
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3269487/
https://ncbi.nlm.nih.gov/pubmed/22058201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2011.051722
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