Autoantibody-Mediated IL-6–Dependent Endothelin-1 Elevation Underlies Pathogenesis in a Mouse Model of Preeclampsia

Preeclampsia (PE) is a life-threatening hypertensive disorder of pregnancy. Elevated circulating endothelin-1 (ET-1) is associated with the disease. However the molecular basis of increased ET-1 production and its role in PE are unknown. This study aimed to investigate the causative factors, patholo...

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Detaylı Bibliyografya
Asıl Yazarlar: Zhou, Cissy Chenyi, Irani, Roxanna A., Dai, Yingbo, Blackwell, Sean C., Hicks, M. John, Ramin, Susan M., Kellems, Rodney E., Xia, Yang
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2011
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3269191/
https://ncbi.nlm.nih.gov/pubmed/21482739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1004026
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