Suppression of microRNA-29 Expression by TGF-β1 Promotes Collagen Expression and Renal Fibrosis

Synthesis and deposition of extracellular matrix (ECM) within the glomerulus and interstitium characterizes renal fibrosis, but the mechanisms underlying this process are incompletely understood. The profibrotic cytokine TGF-β1 modulates the expression of certain microRNAs (miRNAs), suggesting that...

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Detalhes bibliográficos
Main Authors: Wang, Bo, Komers, Radko, Carew, Rosemarie, Winbanks, Catherine E., Xu, Bei, Herman-Edelstein, Michal, Koh, Philip, Thomas, Merlin, Jandeleit-Dahm, Karin, Gregorevic, Paul, Cooper, Mark E., Kantharidis, Phillip
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Nephrology 2012
Assuntos:
Basic Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3269175/
https://ncbi.nlm.nih.gov/pubmed/22095944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2011010055
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