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Coding Constraints Modulate Chemically Spontaneous Mutational Replication Gradients in Mitochondrial Genomes

Distances from heavy and light strand replication origins determine duration mitochondrial DNA remains singlestranded during replication. Hydrolytic deaminations from A->G and C->T occur more on single- than doublestranded DNA. Corresponding replicational nucleotide gradients exist across mito...

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Bibliografiske detaljer
Hovedforfatter: Seligmann, Hervé
Format: Artigo
Sprog:Inglês
Udgivet: Bentham Science Publishers 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3269015/
https://ncbi.nlm.nih.gov/pubmed/22942674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2174/138920212799034802
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