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Detecting Gradients of Asymmetry in Site-Specific Substitutions in Mitochondrial Genomes
During mitochondrial replication, spontaneous mutations occur and accumulate asymmetrically during the time spent single stranded by the heavy strand (D(ssH)). The predominant mutations appear to be deaminations from adenine to hypoxanthine (A → H, which leads to an A → G substitution) and cytosine...
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| Auteurs principaux: | , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2004
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2943950/ https://ncbi.nlm.nih.gov/pubmed/15585129 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/1044549042476901 |
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