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Detecting Gradients of Asymmetry in Site-Specific Substitutions in Mitochondrial Genomes

During mitochondrial replication, spontaneous mutations occur and accumulate asymmetrically during the time spent single stranded by the heavy strand (D(ssH)). The predominant mutations appear to be deaminations from adenine to hypoxanthine (A → H, which leads to an A → G substitution) and cytosine...

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Main Authors: KRISHNAN, NEERAJA M., SELIGMANN, HERVÈ, RAINA, SAMEER Z., POLLOCK, DAVID D.
格式: Artigo
語言:Inglês
出版: 2004
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2943950/
https://ncbi.nlm.nih.gov/pubmed/15585129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/1044549042476901
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