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Detecting Gradients of Asymmetry in Site-Specific Substitutions in Mitochondrial Genomes

During mitochondrial replication, spontaneous mutations occur and accumulate asymmetrically during the time spent single stranded by the heavy strand (D(ssH)). The predominant mutations appear to be deaminations from adenine to hypoxanthine (A → H, which leads to an A → G substitution) and cytosine...

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Detalhes bibliográficos
Main Authors: KRISHNAN, NEERAJA M., SELIGMANN, HERVÈ, RAINA, SAMEER Z., POLLOCK, DAVID D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2943950/
https://ncbi.nlm.nih.gov/pubmed/15585129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/1044549042476901
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