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Detecting Gradients of Asymmetry in Site-Specific Substitutions in Mitochondrial Genomes

During mitochondrial replication, spontaneous mutations occur and accumulate asymmetrically during the time spent single stranded by the heavy strand (D(ssH)). The predominant mutations appear to be deaminations from adenine to hypoxanthine (A → H, which leads to an A → G substitution) and cytosine...

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Autors principals: KRISHNAN, NEERAJA M., SELIGMANN, HERVÈ, RAINA, SAMEER Z., POLLOCK, DAVID D.
Format: Artigo
Idioma:Inglês
Publicat: 2004
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2943950/
https://ncbi.nlm.nih.gov/pubmed/15585129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/1044549042476901
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