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Riluzole and gabapentinoids activate glutamate transporters to facilitate glutamate-induced glutamate release from cultured astrocytes

We have recently demonstrated that the glutamate transporter activator riluzole paradoxically enhanced glutamate-induced glutamate release from cultured astrocytes. We further showed that both riluzole and the α(2)δ subunit ligand gabapentin activated descending inhibition in rats by increasing glut...

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Detalhes bibliográficos
Main Authors: Yoshizumi, Masaru, Eisenach, James. C., Hayashida, Ken-ichiro
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3268950/
https://ncbi.nlm.nih.gov/pubmed/22206816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejphar.2011.12.015
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