IKKα Activation of NOTCH LinksTumorigenesis via FOXA2 Suppression

Pro-inflammatory cytokine TNFα plays critical roles in promoting malignant cell proliferation, angiogenesis, and tumor metastasis in many cancers. However, the mechanism of TNFα-mediated tumor development remains unclear. Here, we show that IKKα, an important downstream kinase of TNFα, interacts wit...

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Hlavní autoři: Liu, Mo, Lee, Dung-Fang, Chen, Chun-Te, Yen, Chia-Jui, Li, Long-Yuan, Lee, Hong-Jen, Chang, Chun-Ju, Chang, Wei-Chao, Hsu, Jung-Mao, Kuo, Hsu-Ping, Xia, Weiya, Wei, Yongkun, Chiu, Pei-Chun, Chou, Chao-Kai, Du, Yi, Dhar, Debanjan, Karin, Michael, Chen, Chung-Hsuan, Hung, Mien-Chie
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3268914/
https://ncbi.nlm.nih.gov/pubmed/22196886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2011.11.018
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