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IKKβ suppression of TSC1 function links the mTOR pathway with insulin resistance
The proinflammatory cytokine TNFα is one of the factors that links obesity-derived chronic inflammation with insulin resistance. Activation of mTOR signaling pathway has been found to suppress insulin sensitivity through serine phosphorylation and the inhibition of IRS1 by mTOR and its downstream ef...
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| Autori principali: | , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2008
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2586899/ https://ncbi.nlm.nih.gov/pubmed/18949383 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijmm_00000065 |
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