Streptococcal M1 protein constructs a pathological host fibrinogen network

M1 protein, a major virulence factor of the leading invasive strain of group A Streptococcus, is sufficient to induce toxic shock-like vascular leakage and tissue injury. These events are triggered by the formation of a complex between M1 and fibrinogen (Fg) that, unlike M1 or Fg alone, leads to neu...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Macheboeuf, Pauline, Buffalo, Cosmo, Fu, Chi-yu, Zinkernagel, Annelies S., Cole, Jason N., Johnson, John E., Nizet, Victor, Ghosh, Partho
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3268815/
https://ncbi.nlm.nih.gov/pubmed/21475196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature09967
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky