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Uracil DNa-glycosylase from HeLa cells: general properties, substrate specificity and effect of uracil analogs.

Uracil-DNA glycosylase was partially purified from HeLa cells. Various substrates containing [3H]dUMP residues were prepared by nick-translation of calf thymus DNA. The standard substrate was double-stranded DNA with [3H]dUMP located internally in the chain. Compared to the release of uracil from th...

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Détails bibliographiques
Auteurs principaux: Krokan, H, Wittwer, C U
Format: Artigo
Langue:Inglês
Publié: 1981
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC326875/
https://ncbi.nlm.nih.gov/pubmed/7279657
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