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Hybrid Modeling of Cell Signaling and Transcriptional Reprogramming and Its Application in C. elegans Development

Modeling of signal driven transcriptional reprogramming is critical for understanding of organism development, human disease, and cell biology. Many current modeling techniques discount key features of the biological sub-systems when modeling multiscale, organism-level processes. We present a mechan...

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Detalhes bibliográficos
Main Authors: Fertig, Elana J., Danilova, Ludmila V., Favorov, Alexander V., Ochs, Michael F.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Research Foundation 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3268630/
https://ncbi.nlm.nih.gov/pubmed/22303372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2011.00077
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