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CpG island methylator phenotype associates with low-degree chromosomal abnormalities in colorectal cancer

PURPOSE: Aberrant promoter methylation and genomic instability occur frequently during colorectal cancer (CRC) development. CpG island methylator phenotype (CIMP) has been shown to associate with microsatellite instability, BRAF mutation and often found in the right-side colon. Nevertheless, the rel...

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Main Authors: Cheng, Yu-Wei, Pincas, Hanna, Bacolod, Manny, Schemmann, Gunter, Giardina, Sarah F., Huang, Jianmin, Barral, Sandra, Idrees, Kamran, Khan, Sajid A., Zeng, Zhaoshi, Rosenberg, Shoshana, Notterman, Daniel A., Ott, Jurg, Paty, Philip, Barany, Francis
Format: Artigo
Jezik:Inglês
Izdano: 2008
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3268558/
https://ncbi.nlm.nih.gov/pubmed/18829479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-08-0216
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