CpG island methylator phenotype associates with low-degree chromosomal abnormalities in colorectal cancer

PURPOSE: Aberrant promoter methylation and genomic instability occur frequently during colorectal cancer (CRC) development. CpG island methylator phenotype (CIMP) has been shown to associate with microsatellite instability, BRAF mutation and often found in the right-side colon. Nevertheless, the rel...

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Autores principales: Cheng, Yu-Wei, Pincas, Hanna, Bacolod, Manny, Schemmann, Gunter, Giardina, Sarah F., Huang, Jianmin, Barral, Sandra, Idrees, Kamran, Khan, Sajid A., Zeng, Zhaoshi, Rosenberg, Shoshana, Notterman, Daniel A., Ott, Jurg, Paty, Philip, Barany, Francis
Formato: Artigo
Lenguaje:Inglês
Publicado: 2008
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3268558/
https://ncbi.nlm.nih.gov/pubmed/18829479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-08-0216
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