Post-translational Modification by β-Lysylation Is Required for Activity of Escherichia coli Elongation Factor P (EF-P)

Bacterial elongation factor P (EF-P) is the ortholog of archaeal and eukaryotic initiation factor 5A (eIF5A). EF-P shares sequence homology and crystal structure with eIF5A, but unlike eIF5A, EF-P does not undergo hypusine modification. Recently, two bacterial genes, yjeA and yjeK, encoding truncate...

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Autores principales: Park, Jong-Hwan, Johansson, Hans E., Aoki, Hiroyuki, Huang, Bill X., Kim, Hee-Yong, Ganoza, M. Clelia, Park, Myung Hee
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2012
Materias:
Protein Synthesis and Degradation
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3268417/
https://ncbi.nlm.nih.gov/pubmed/22128152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.309633
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