(R)-β-Lysine-modified Elongation Factor P Functions in Translation Elongation

Post-translational modification of bacterial elongation factor P (EF-P) with (R)-β-lysine at a conserved lysine residue activates the protein in vivo and increases puromycin reactivity of the ribosome in vitro. The additional hydroxylation of EF-P at the same lysine residue by the YfcM protein has a...

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Autores principales: Bullwinkle, Tammy J., Zou, S. Betty, Rajkovic, Andrei, Hersch, Steven J., Elgamal, Sara, Robinson, Nathaniel, Smil, David, Bolshan, Yuri, Navarre, William Wiley, Ibba, Michael
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2013
Materias:
Protein Synthesis and Degradation
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3567691/
https://ncbi.nlm.nih.gov/pubmed/23277358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.438879
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