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Cherubism Gene Sh3bp2 is Important for Optimal Bone Formation, Osteoblast Differentiation and Function

INTRODUCTION: Cherubism is a human genetic disorder that causes bilateral symmetrical enlargement of the maxilla and mandible in children. It is caused by mutations in SH3BP2. The exact pathogenesis of the disorder is an area of active research. Sh3bp2 knock-in mice were developed by introducing a P...

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Detalhes bibliográficos
Main Authors: Mukherjee, Padma M., Wang, Chiachien J., Chen, I-Ping, Jafarov, Toghrul, Olsen, Bjorn R., Ueki, Yasuyoshi, Reichenberger, Ernst J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3268358/
https://ncbi.nlm.nih.gov/pubmed/20691350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajodo.2009.05.021
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