Lipidomic discovery of deoxysiderophores reveals a revised mycobactin biosynthesis pathway in Mycobacterium tuberculosis

To measure molecular changes underlying pathogen adaptation, we generated a searchable dataset of more than 12,000 mass spectrometry events, corresponding to lipids and small molecules that constitute a lipidome for Mycobacterium tuberculosis. Iron is essential for M. tuberculosis survival, and the...

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Bibliographische Detailangaben
Hauptverfasser: Madigan, Cressida A., Cheng, Tan-Yun, Layre, Emilie, Young, David C., McConnell, Matthew J., Debono, C. Anthony, Murry, Jeffrey P., Wei, Jun-Rong, Barry, Clifton E., Rodriguez, G. Marcela, Matsunaga, Isamu, Rubin, Eric J., Moody, D. Branch
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2012
Schlagworte:
Biological Sciences
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3268331/
https://ncbi.nlm.nih.gov/pubmed/22232695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1109958109
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