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Drosophila RNA polymerase III repressor Maf1 controls body size and developmental timing by modulating tRNA(i)(Met) synthesis and systemic insulin signaling
The target-of-rapamycin pathway couples nutrient availability with tissue and organismal growth in metazoans. The key effectors underlying this growth are, however, unclear. Here we show that Maf1, a repressor of RNA polymerase III-dependent tRNA transcription, is an important mediator of nutrient-d...
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| Asıl Yazarlar: | , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
National Academy of Sciences
2012
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3268294/ https://ncbi.nlm.nih.gov/pubmed/22228302 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1113311109 |
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