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Maf1 Protein, Repressor of RNA Polymerase III, Indirectly Affects tRNA Processing

Maf1 is negative regulator of RNA polymerase III in yeast. We observed high levels of both primary transcript and end-matured, intron-containing pre-tRNAs in the maf1Δ strain. This pre-tRNA accumulation could be overcome by transcription inhibition, arguing against a direct role of Maf1 in tRNA matu...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Karkusiewicz, Iwona, Turowski, Tomasz W., Graczyk, Damian, Towpik, Joanna, Dhungel, Nripesh, Hopper, Anita K., Boguta, Magdalena
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2011
Schlagworte:
RNA
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3234771/
https://ncbi.nlm.nih.gov/pubmed/21940626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.253310
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