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Maf1-mediated repression of RNA polymerase III transcription inhibits tRNA degradation via RTD pathway

tRNA precursors, which are transcribed by RNA polymerase III, undergo end-maturation, splicing, and base modifications. Hypomodified tRNAs, such as tRNA(Val(AAC)), lacking 7-methylguanosine and 5-methylcytidine modifications, are subject to degradation by a rapid tRNA decay pathway. Here we searched...

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Hlavní autoři: Turowski, Tomasz W., Karkusiewicz, Iwona, Kowal, Justyna, Boguta, Magdalena
Médium: Artigo
Jazyk:Inglês
Vydáno: Cold Spring Harbor Laboratory Press 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3446706/
https://ncbi.nlm.nih.gov/pubmed/22919049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.033597.112
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