T helper cell- and CD40-dependent germline IgM prevents chronic virus-induced demyelinating disease

Generation of antiviral IgM is usually considered as a marker of a short-lived initial antibody response that is replaced by hypermutated and more-efficient IgG. However, once viruses have established a particular niche for their persistence (e.g., within the CNS), the immune system has to specifica...

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Bibliografiske detaljer
Main Authors: Gil-Cruz, Cristina, Perez-Shibayama, Christian, Firner, Sonja, Waisman, Ari, Bechmann, Ingo, Thiel, Volker, Cervantes-Barragan, Luisa, Ludewig, Burkhard
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2012
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3268283/
https://ncbi.nlm.nih.gov/pubmed/22232667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1115154109
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