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T helper cell- and CD40-dependent germline IgM prevents chronic virus-induced demyelinating disease
Generation of antiviral IgM is usually considered as a marker of a short-lived initial antibody response that is replaced by hypermutated and more-efficient IgG. However, once viruses have established a particular niche for their persistence (e.g., within the CNS), the immune system has to specifica...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3268283/ https://ncbi.nlm.nih.gov/pubmed/22232667 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1115154109 |
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