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Absence of CD40–CD40 ligand interactions in X-linked hyper-IgM syndrome does not affect differentiation of T helper cell subsets

The aim of this study was to investigate the effect of absent CD40–CD40 ligand interactions in patients with X-linked hyper–IgM syndrome (XHIGM) on the generation of Th1 and Th2 immunity. Whole blood from patients and sex- and age-matched controls was stimulated with phorbol myristate acetate (PMA)...

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Detalhes bibliográficos
Main Authors: Uronen, H, Callard, R E
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1905692/
https://ncbi.nlm.nih.gov/pubmed/10931152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2249.2000.01307.x
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