Загрузка...

(R)-α-Lipoic Acid Treatment Restores Ceramide Balance in Aging Rat Cardiac Mitochondria

Inflammation results in heightened mitochondrial ceramide levels, which cause electron transport chain dysfunction, elevates reactive oxygen species, and increases apoptosis. As mitochondria in aged hearts also display many of these characteristics, we hypothesized that mitochondrial decay stems par...

Полное описание

Сохранить в:
Библиографические подробности
Главные авторы: Monette, Jeffrey S., Gómez, Luis A., Moreau, Régis F., Dunn, Kevin C., Butler, Judy A., Finlay, Liam A., Michels, Alexander J., Shay, Kate Petersen, Smith, Eric J., Hagen, Tory M.
Формат: Artigo
Язык:Inglês
Опубликовано: 2010
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3268156/
https://ncbi.nlm.nih.gov/pubmed/20934512
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.phrs.2010.09.007
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!