Caricamento...

DNA Strand Cleaving Properties and Hypoxia-Selective Cytotoxicity of 7-Chloro-2-thienylcarbonyl-3-trifluoromethylquinoxaline 1,4-Dioxide

The heterocyclic N-oxide, 3-amino-1,2,4-benzotriazine 1,4-dioxide (tirapazamine, 1), shows promising antitumor activity in preclinical studies, but there is a continuing need to explore new compounds in this general structural category. In the work described here, we examined the properties of 7-chl...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Junnotula, Venkatraman, Rajapakse, Anuruddha, Arbillaga, Leire, de Cerain, Adela López, Solano, Beatriz, Villar, Raquel, Monge, Antonio, Gates, Kent S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3268132/
https://ncbi.nlm.nih.gov/pubmed/20371184
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2010.03.042
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !