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Hypoxia-selective, enzymatic conversion of 6-nitroquinoline into a fluorescent helicene: pyrido[3,2-f]quinolino[6,5-c]cinnoline 3-oxide

Regions of low oxygen concentration (hypoxia) occur in both normal human physiology and under pathophysiological conditions. Fluorescent probes for the direct imaging of cellular hypoxia could be useful tools that complement radiochemical imaging and immunohistochemical staining methods. In this wor...

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Hlavní autoři: Rajapakse, Anuruddha, Gates, Kent S.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3360953/
https://ncbi.nlm.nih.gov/pubmed/22417220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jo3004748
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