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Hypoxia-selective, enzymatic conversion of 6-nitroquinoline into a fluorescent helicene: pyrido[3,2-f]quinolino[6,5-c]cinnoline 3-oxide

Regions of low oxygen concentration (hypoxia) occur in both normal human physiology and under pathophysiological conditions. Fluorescent probes for the direct imaging of cellular hypoxia could be useful tools that complement radiochemical imaging and immunohistochemical staining methods. In this wor...

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Detalhes bibliográficos
Main Authors: Rajapakse, Anuruddha, Gates, Kent S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3360953/
https://ncbi.nlm.nih.gov/pubmed/22417220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jo3004748
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