Correlation Between Quantitative HER-2 Protein Expression and Risk for Brain Metastases in HER-2(+) Advanced Breast Cancer Patients Receiving Trastuzumab-Containing Therapy

BACKGROUND. Patients with human epidermal growth factor receptor (HER)-2(+) breast cancer are at particularly high risk for brain metastases; however, the biological basis is not fully understood. Using a novel HER-2 assay, we investigated the correlation between quantitative HER-2 expression in pri...

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Detalhes bibliográficos
Main Authors: Duchnowska, Renata, Biernat, Wojciech, Szostakiewicz, Barbara, Sperinde, Jeff, Piette, Fanny, Haddad, Mojgan, Paquet, Agnes, Lie, Yolanda, Czartoryska-Arłukowicz, Bogumiła, Wysocki, Piotr, Jankowski, Tomasz, Radecka, Barbara, Foszczyńska-Kłoda, Małgorzata, Litwiniuk, Maria, Dȩbska, Sylwia, Weidler, Jodi, Huang, Weidong, Buyse, Marc, Bates, Michael, Jassem, Jacek
Formato: Artigo
Idioma:Inglês
Publicado em: AlphaMed Press 2012
Assuntos:
Breast Cancer
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3267818/
https://ncbi.nlm.nih.gov/pubmed/22234627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1634/theoncologist.2011-0212
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