Immunohistochemical prediction of lapatinib efficacy in advanced HER2-positive breast cancer patients

Molecular mechanisms of lapatinib resistance in breast cancer are not well understood. The aim of this study was to correlate expression of selected proteins involved in ErbB family signaling pathways with clinical efficacy of lapatinib. Study group included 270 HER2-positive advanced breast cancer...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Duchnowska, Renata, Wysocki, Piotr J., Korski, Konstanty, Czartoryska-Arłukowicz, Bogumiła, Niwińska, Anna, Orlikowska, Marlena, Radecka, Barbara, Studziński, Maciej, Demlova, Regina, Ziółkowska, Barbara, Merdalska, Monika, Hajac, Łukasz, Myśliwiec, Paulina, Zuziak, Dorota, Dębska-Szmich, Sylwia, Lang, Istvan, Foszczyńska-Kłoda, Małgorzata, Karczmarek-Borowska, Bożenna, Żawrocki, Anton, Kowalczyk, Anna, Biernat, Wojciech, Jassem, Jacek
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4808017/
https://ncbi.nlm.nih.gov/pubmed/26623720
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