Antibody targeting of Cathepsin S induces antibody-dependent cellular cytotoxicity

BACKGROUND: Proteolytic enzymes have been implicated in driving tumor progression by means of their cancer cell microenvironment activity where they promote proliferation, differentiation, apoptosis, migration, and invasion. Therapeutic strategies have focused on attenuating their activity using sma...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Kwok, Hang Fai, Buick, Richard J, Kuehn, Diana, Gormley, Julie A, Doherty, Declan, Jaquin, Thomas J, McClurg, Angela, Ward, Claire, Byrne, Teresa, Jaworski, Jacob, Leung, Ka Lai, Snoddy, Philip, McAnally, Christine, Burden, Roberta E, Gray, Breena, Lowry, Jenny, Sermadiras, Isabelle, Gruszka, Natalia, Courtenay-Luck, Nigel, Kissenpfennig, Adrien, Scott, Christopher J, Johnston, James A, Olwill, Shane A
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2011
Sujets:
Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3267679/
https://ncbi.nlm.nih.gov/pubmed/22168338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-10-147
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