Antibody targeting of Cathepsin S induces antibody-dependent cellular cytotoxicity

BACKGROUND: Proteolytic enzymes have been implicated in driving tumor progression by means of their cancer cell microenvironment activity where they promote proliferation, differentiation, apoptosis, migration, and invasion. Therapeutic strategies have focused on attenuating their activity using sma...

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Detalhes bibliográficos
Main Authors: Kwok, Hang Fai, Buick, Richard J, Kuehn, Diana, Gormley, Julie A, Doherty, Declan, Jaquin, Thomas J, McClurg, Angela, Ward, Claire, Byrne, Teresa, Jaworski, Jacob, Leung, Ka Lai, Snoddy, Philip, McAnally, Christine, Burden, Roberta E, Gray, Breena, Lowry, Jenny, Sermadiras, Isabelle, Gruszka, Natalia, Courtenay-Luck, Nigel, Kissenpfennig, Adrien, Scott, Christopher J, Johnston, James A, Olwill, Shane A
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3267679/
https://ncbi.nlm.nih.gov/pubmed/22168338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-10-147
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