Calcitonin gene-related peptide promotes cellular changes in trigeminal neurons and glia implicated in peripheral and central sensitization

BACKGROUND: Calcitonin gene-related peptide (CGRP), a neuropeptide released from trigeminal nerves, is implicated in the underlying pathology of temporomandibular joint disorder (TMD). Elevated levels of CGRP in the joint capsule correlate with inflammation and pain. CGRP mediates neurogenic inflamm...

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Main Authors: Cady, Ryan J, Glenn, Joseph R, Smith, Kael M, Durham, Paul L
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2011
Assuntos:
Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3267674/
https://ncbi.nlm.nih.gov/pubmed/22145886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1744-8069-7-94
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