Calcitonin gene-related peptide promotes cellular changes in trigeminal neurons and glia implicated in peripheral and central sensitization

BACKGROUND: Calcitonin gene-related peptide (CGRP), a neuropeptide released from trigeminal nerves, is implicated in the underlying pathology of temporomandibular joint disorder (TMD). Elevated levels of CGRP in the joint capsule correlate with inflammation and pain. CGRP mediates neurogenic inflamm...

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Bibliographische Detailangaben
Hauptverfasser: Cady, Ryan J, Glenn, Joseph R, Smith, Kael M, Durham, Paul L
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2011
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3267674/
https://ncbi.nlm.nih.gov/pubmed/22145886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1744-8069-7-94
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