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Epigenetic regulation of the calcitonin gene–related peptide gene in trigeminal glia

BACKGROUND: The neuropeptide calcitonin gene–related peptide (CGRP) plays a key role in migraine. CGRP gene expression involves an enhancer that is active in neurons, yet inactive in glia. In this report, we analyze epigenetic modifications that allow enhancer activation in glia. METHODS: DNA methyl...

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Autors principals: Park, Ki-Youb, Fletcher, Joshua R, Raddant, Ann C, Russo, Andrew F
Format: Artigo
Idioma:Inglês
Publicat: 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3383834/
https://ncbi.nlm.nih.gov/pubmed/21216873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0333102410391487
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