Angiotensin receptor agonistic autoantibodies induce pre-eclampsia in pregnant mice

Pre-eclampsia affects approximately 5% of pregnancies and remains a leading cause of maternal and neonatal mortality and morbidity in the United States and the world(1,2). The clinical hallmarks of this maternal disorder include hypertension, proteinuria, endothelial dysfunction and placental defect...

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Main Authors: Zhou, Cissy C, Zhang, Yujin, Irani, Roxanna A, Zhang, Hong, Mi, Tiejuan, Popek, Edwina J, Hicks, M John, Ramin, Susan M, Kellems, Rodney E, Xia, Yang
Format: Artigo
Sprog:Inglês
Udgivet: 2008
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3267158/
https://ncbi.nlm.nih.gov/pubmed/18660815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.1856
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