Recombinant Vascular Endothelial Growth Factor 121 Attenuates Autoantibody-Induced Features of Pre-eclampsia in Pregnant Mice

BACKGROUND: Pre-eclampsia (PE) is a serious hypertensive disorder of pregnancy characterized by excessive production of a soluble form of the vascular endothelial growth factor (VEGF) receptor-1, termed soluble fms-like tyrosine kinase-1 (sFlt-1). This placental-derived factor is believed to be a ke...

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Hlavní autoři: Siddiqui, Athar H., Irani, Roxanna A., Zhang, Yujin, Dai, Yingbo, Blackwell, Sean C., Ramin, Susan M., Kellems, Rodney E., Xia, Yang
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3262171/
https://ncbi.nlm.nih.gov/pubmed/21183928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ajh.2010.247
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