Heterogeneous amplification of ERBB2 in primary lesions is responsible for the discordant ERBB2 status of primary and metastatic lesions in gastric carcinoma

AIMS: To determine the extent of HER2 homogeneity/heterogeneity in primary versus metastatic gastric carcinoma (GC). MATERIALS AND RESULTS: The human epidermal growth factor receptor 2 (HER2) status in primary and metastatic lesions was evaluated by immunohistochemistry (IHC) and fluorescence in-sit...

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Autores principales: Kim, Min A, Lee, Hyuk-Joon, Yang, Han-Kwang, Bang, Yung-Jue, Kim, Woo Ho
Formato: Artigo
Lenguaje:Inglês
Publicado: Blackwell Publishing Ltd 2011
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Original Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3267049/
https://ncbi.nlm.nih.gov/pubmed/22092393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2559.2011.04012.x
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