Distinct tumor immune microenvironments in primary and metastatic lesions in gastric cancer patients

This study compared the tumor immune microenvironments (TIMEs) of primary gastric cancer (PGC) and paired metastatic gastric cancer (MGC). CD4(+) and CD8(+) T-cell density and PD-L1 expression were evaluated by multiplex immunohistochemistry, DNA mismatch repair (MMR) by immunohistochemistry, and im...

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Publicado en:Sci Rep
Main Authors: Son, Seung-Myoung, Woo, Chang Gok, Kim, Dae Hoon, Yun, Hyo Yung, Kim, Hongsik, Kim, Hee Kyung, Yang, Yaewon, Kwon, Jihyun, Kwon, Minsuk, Kim, Tae-Yong, Kim, Hyung-Don, Koh, June-Young, Park, Su-Hyung, Shin, Eui-Cheol, Han, Hye Sook
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2020
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7459099/
https://ncbi.nlm.nih.gov/pubmed/32868848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-71340-z
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