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Distinct tumor immune microenvironments in primary and metastatic lesions in gastric cancer patients

This study compared the tumor immune microenvironments (TIMEs) of primary gastric cancer (PGC) and paired metastatic gastric cancer (MGC). CD4(+) and CD8(+) T-cell density and PD-L1 expression were evaluated by multiplex immunohistochemistry, DNA mismatch repair (MMR) by immunohistochemistry, and im...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Son, Seung-Myoung, Woo, Chang Gok, Kim, Dae Hoon, Yun, Hyo Yung, Kim, Hongsik, Kim, Hee Kyung, Yang, Yaewon, Kwon, Jihyun, Kwon, Minsuk, Kim, Tae-Yong, Kim, Hyung-Don, Koh, June-Young, Park, Su-Hyung, Shin, Eui-Cheol, Han, Hye Sook
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7459099/
https://ncbi.nlm.nih.gov/pubmed/32868848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-71340-z
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