Structure of a Blinkin-BUBR1 Complex Reveals an Interaction Crucial for Kinetochore-Mitotic Checkpoint Regulation via an Unanticipated Binding Site

The maintenance of genomic stability relies on the spindle assembly checkpoint (SAC), which ensures accurate chromosome segregation by delaying the onset of anaphase until all chromosomes are properly bioriented and attached to the mitotic spindle. BUB1 and BUBR1 kinases are central for this process...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Bolanos-Garcia, Victor M., Lischetti, Tiziana, Matak-Vinković, Dijana, Cota, Ernesto, Simpson, Pete J., Chirgadze, Dimitri Y., Spring, David R., Robinson, Carol V., Nilsson, Jakob, Blundell, Tom L.
Format: Artigo
Sprog:Inglês
Udgivet: Cell Press 2011
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3267040/
https://ncbi.nlm.nih.gov/pubmed/22000412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2011.09.017
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker