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The Intracellular DNA Sensor IFI16 Gene Acts as Restriction Factor for Human Cytomegalovirus Replication

Human interferon (IFN)-inducible IFI16 protein, an innate immune sensor of intracellular DNA, modulates various cell functions, however, its role in regulating virus growth remains unresolved. Here, we adopt two approaches to investigate whether IFI16 exerts pro- and/or anti-viral actions. First, th...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Gariano, Grazia Rosaria, Dell'Oste, Valentina, Bronzini, Matteo, Gatti, Deborah, Luganini, Anna, De Andrea, Marco, Gribaudo, Giorgio, Gariglio, Marisa, Landolfo, Santo
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Public Library of Science 2012
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3266931/
https://ncbi.nlm.nih.gov/pubmed/22291595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1002498
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