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The Intracellular DNA Sensor IFI16 Gene Acts as Restriction Factor for Human Cytomegalovirus Replication

Human interferon (IFN)-inducible IFI16 protein, an innate immune sensor of intracellular DNA, modulates various cell functions, however, its role in regulating virus growth remains unresolved. Here, we adopt two approaches to investigate whether IFI16 exerts pro- and/or anti-viral actions. First, th...

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Bibliografski detalji
Glavni autori: Gariano, Grazia Rosaria, Dell'Oste, Valentina, Bronzini, Matteo, Gatti, Deborah, Luganini, Anna, De Andrea, Marco, Gribaudo, Giorgio, Gariglio, Marisa, Landolfo, Santo
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2012
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3266931/
https://ncbi.nlm.nih.gov/pubmed/22291595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1002498
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