Recurrent genomic instability of chromosome 1q in neural derivatives of human embryonic stem cells

Human pluripotent stem cells offer a limitless source of cells for regenerative medicine. Neural derivatives of human embryonic stem cells (hESCs) are currently being used for cell therapy in 3 clinical trials. However, hESCs are prone to genomic instability, which could limit their clinical utility...

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Detalhes bibliográficos
Main Authors: Varela, Christine, Denis, Jérôme Alexandre, Polentes, Jérôme, Feyeux, Maxime, Aubert, Sophie, Champon, Benoite, Piétu, Geneviève, Peschanski, Marc, Lefort, Nathalie
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3266775/
https://ncbi.nlm.nih.gov/pubmed/22269325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI46268
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