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Diblock copolymers with tunable pH transitions for gene delivery

A series of diblock copolymers containing an endosomal-releasing segment composed of diethylaminoethyl methacrylate (DEAEMA) and butyl methacrylate (BMA) were synthesized via reversible addition-fragmentation chain transfer (RAFT) polymerization. The materials were designed to condense plasmid DNA (...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Manganiello, M.J., Cheng, C., Convertine, A.J., Bryers, J.D., Stayton, P.S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3266685/
https://ncbi.nlm.nih.gov/pubmed/22169826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2011.11.019
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