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Phospholipid scramblase 1 mediates type I interferon-induced protection against staphylococcal α-toxin

The opportunistic gram-positive pathogen Staphylococcus aureus is a leading cause of pneumonia and sepsis. Staphylococcal α-toxin, a prototypical pore-forming toxin, is a major virulence factor of S. aureus clinical isolates and lung epithelial cells are highly sensitive to α-toxin's cytolytic...

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Detalhes bibliográficos
Main Authors: Lizak, Miroslaw, Yarovinsky, Timur O.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3266557/
https://ncbi.nlm.nih.gov/pubmed/22264514
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2011.12.004
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