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STAT3 Cooperates With Phospholipid Scramblase 2 to Suppress Type I Interferon Response

Type I interferon (IFN-I) is a pluripotent cytokine that modulates innate and adaptive immunity. We have previously shown that STAT3 suppresses IFN-I response in a manner dependent on its N-terminal domain (NTD), but independent of its DNA-binding and transactivation ability. Using the yeast two-hyb...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Tsai, Ming-Hsun, Lee, Chien-Kuo
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6104169/
https://ncbi.nlm.nih.gov/pubmed/30158934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.01886
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