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Phosphoinositide Signaling Regulates the Exocyst Complex and Polarized Integrin Trafficking in Directionally Migrating Cells

Polarized delivery of signaling and adhesion molecules to the leading edge is required for directional migration of cells. Here, we describe a role for the PIP(2) synthesizing enzyme, PIPKIγi2, in regulation of exocyst complex control of cell polarity and polarized integrin trafficking during migrat...

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Hlavní autoři: Thapa, Narendra, Sun, Yue, Schramp, Mark, Choi, Suyoung, Ling, Kun, Anderson, Richard A
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3266520/
https://ncbi.nlm.nih.gov/pubmed/22264730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2011.10.030
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